NM-Carbomer as Excipients for Topical Application
Topical drug delivery offers a safe, more convenient
treatment option for a variety of disorders when compared to systemic dosage
forms.
Topical drug delivery can include dermal,
nasal, ocular, rectal, and vaginal routes of administration. Liquid
solutions and suspensions as well as semisolids such as creams,
lotions, ointments, and gels are common topical drug delivery formats for a
variety of indications.
Anhui Newman Fine Chemicals Co., LTd
has extensive experience supplying best-in-class bioadhesive excipients that
support topical drug products. Whether developing an over-the-counter product
or prescription drug formulation, Anhui Newman is a comprehensive partner in
the topical drug delivery space.
NM-Carbomer products have been
used extensively in the development of safe and effective topical products.
These excipients provide critical qualities to address market needs, including:
Ideal
Aesthetic and Sensory Qualities – increase patient compliance
through low-irritation, aesthetically pleasing formulations with optimal feel
Bioadhesion
/ Mucoadhesion – optimize drug delivery by prolonging product contact with
biological membranes, improve patient compliance via reduced need for frequent
drug administration, and protect and lubricate mucosal surfaces
Efficient
Rheology Modification and thickening for topical
semisolids
NM-Carbomers listed in the table
below are suitable for use in topical applications and are present in
commercialized topical products.
|
NM-Carbomers as Excipients
for Topical Application
|
|
Product
Trade Name
|
Polymerization
Solvents1
|
China
(ChP)
|
Europe
(Ph. Eur.)
|
United States
(USP/NF)
|
|
NM-Carbomer
981G
|
Cosolvent
|
Carbomer Homopolymer
Type A
|
Carbomers
|
Carbomer Homopolymer
Type A
|
|
NM-Carbomer
980G
|
Cosolvent
|
Carbomer Homopolymer
Type C
|
Carbomers
|
Carbomer Homopolymer
Type C
|
|
NM-Carbomer
971P
|
Ethyl Acetate
|
Carbomer Homopolymer
Type A
|
Carbomers
|
Carbomer Homopolymer
Type A
|
|
NM-Carbomer
974P
|
Ethyl Acetate
|
Carbomer Homopolymer
Type B
|
Carbomers
|
Carbomer Homopolymer
Type B
|
|
NM-Carbomer
71G
|
Ethyl Acetate
|
Carbomer Homopolymer
Type A
|
Carbomers
|
Carbomer Homopolymer
Type A
|
|
NM-Carbomer
934P
|
Cosolvent
|
Carbomer Homopolymer
Type B
|
Carbomers
|
Carbomer Homopolymer
Type B
|
|
NM-Carbomer
2020G
|
Cosolvent
|
Carbomer Interpolymer
Type B
|
_
|
Carbomer Interpolymer
Type B
|
|
NM-Carbomer
10G
|
Cosolvent
|
Carbomer Interpolymer
Type A
|
_
|
Carbomer Interpolymer
Type A
|
|
NM-Carbomer
1382G
|
CoSolvent
|
Carbomer Copolymer
Type B
|
_
|
Carbomer Copolymer
Type B
|
|
NM-Carbomer
TR-1 P
|
Cosolvent
|
Carbomer Copolymer
Type B
|
_
|
Carbomer Copolymer
Type B
|
|
NM-Carbomer
TR-2 P
|
Cosolvent
|
Carbomer Copolymer
TypeA
|
_
|
Carbomer Copolymer
TypeA
|
1Cosolvent = mixture of
Ethyl acetate (class III solvent) and Cyclohexane (class II solvent)
-
Carbomer Homopolymer Type B
Carbomer Homopolymer Type B
Including
NM-Carbomer 934P, NM-Carbomer974P
And meets the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type B
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type B
Japanese Pharmaceutical Excipients (JPE) Monograph for Carboxyvinyl Polymer
General Product Characteristics
Appearance: White, fluffy powder
Odor: Slightly acetic
Read More
-
Carbomer Copolymer Type B
Carbomer Copolymer Type B
Including NM-Carbomer TR-1P, and NM-Carbomer 1382G
And meeting the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer
Copolymer Type B
China Pharmacopeia (ChP) monograph for Carbomer Copolymer Type B
General Product Characteristics
Appearance: White fluffy powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 1382G
NM-Carbomer
1382G
NM-Carbomer
1382G meets the current
edition of the following monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer
Copolymer Type B
China
Pharmacopeia (ChP) monograph for Carbomer Copolymer Type B
General
Product Characteristics
Appearance: White fluffy
powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 981G
NM-Carbomer 981G
NM-Carbomer 981G meets the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type A (Note: The previous USP/NF compendial name for this product was Carbomer 941.)
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type A
General Product Characteristics
Appearance: White fluffy powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 971P
NM-Carbomer 971P
NM-Carbomer971P meets the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type A
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type A
General Product Characteristics
Appearance: White, fluffy powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 980G
NM-Carbomer 980G
NM-Carbomer 980G meets the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type C (Note: The previous USP/NF compendial name for this product was Carbomer 980.)
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type C
General Product Characteristics
Appearance: White fluffy powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 934P
NM-Carbomer 934P
NM-Carbomer 934P meets the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type B
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
Chinese Pharmacopoeia (ChP.) monograph for Carbomer Homopolymer Type B
INCI Name: Carbomer
Appearance: White fluffy powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 974P
NM-Carbomer 974P
NM-Carbomer
974P meets the current
edition of the following monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer Homopolymer Type B(Note: The
previous USP/NF compendial name for this product was Carbomer 934P.)
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
Chinese
Pharmacopoeia (ChP.) monograph
for Carbomer Homopolymer Type B
General Product Characteristic
Appearance: White fluffy
powder
Odor: Slightly acetic
Read More
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